Chronic low-level expression of HIV-1 Tat promotes a neurodegenerative phenotype with aging

Chronic low-level expression of HIV-1 Tat promotes a neurodegenerative phenotype with aging

Abstract The widespread use of combinational antiretroviral therapies (cART) in developed countries has changed the course of Human Immunodeficiency Virus (HIV) infection from an almost universally fatal disease to a chronic infection for the majority of individuals. Although cART has reduced the se...

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Bibliographic Details
Main Authors: Alex M. Dickens, Seung Wan Yoo, Alfred C. Chin, Jiadi Xu, Tory P. Johnson, Amanda L. Trout, Kurt F. Hauser, Norman J. Haughey
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07570-5

Internet

https://doi.org/10.1038/s41598-017-07570-5

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