Chronic low-level expression of HIV-1 Tat promotes a neurodegenerative phenotype with aging
Abstract The widespread use of combinational antiretroviral therapies (cART) in developed countries has changed the course of Human Immunodeficiency Virus (HIV) infection from an almost universally fatal disease to a chronic infection for the majority of individuals. Although cART has reduced the se...
Main Authors: | Alex M. Dickens, Seung Wan Yoo, Alfred C. Chin, Jiadi Xu, Tory P. Johnson, Amanda L. Trout, Kurt F. Hauser, Norman J. Haughey |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-08-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-07570-5 |
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