HLA and non-HLA genes and familial predisposition to autoimmune diseases in families with a child affected by type 1 diabetes.

HLA and non-HLA genes and familial predisposition to autoimmune diseases in families with a child affected by type 1 diabetes.

Genetic predisposition could be assumed to be causing clustering of autoimmunity in individuals and families. We tested whether HLA and non-HLA loci associate with such clustering of autoimmunity. We included 1,745 children with type 1 diabetes from the Finnish Pediatric Diabetes Register. Data on p...

Full description

Bibliographic Details
Main Authors: Anna Parkkola, Antti-Pekka Laine, Markku Karhunen, Taina Härkönen, Samppa J Ryhänen, Jorma Ilonen, Mikael Knip, Finnish Pediatric Diabetes Register
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5705143?pdf=render

Internet

http://europepmc.org/articles/PMC5705143?pdf=render

Similar Items