Silencing of diphthamide synthesis 3 (Dph3) reduces metastasis of murine melanoma.

Melanoma is the most dangerous skin cancer due to its highly metastatic potential and resistance to chemotherapy. Currently, there is no effective treatment for melanoma once it is progressed to metastatic stage. Therefore, further study to elucidate the molecular mechanism underlying the metastasis...

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Bibliographic Details
Main Authors: Lei Wang, Yu Shi, Peijun Ju, Rui Liu, Siok Ping Yeo, Yinyan Xia, Hamed Owlanj, Zhiwei Feng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3502187?pdf=render