Tomosyn inhibits synaptic vesicle priming in Caenorhabditis elegans.

Tomosyn inhibits synaptic vesicle priming in Caenorhabditis elegans.

Caenorhabditis elegans TOM-1 is orthologous to vertebrate tomosyn, a cytosolic syntaxin-binding protein implicated in the modulation of both constitutive and regulated exocytosis. To investigate how TOM-1 regulates exocytosis of synaptic vesicles in vivo, we analyzed C. elegans tom-1 mutants. Our el...

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Bibliographic Details
Main Authors: Elena O Gracheva, Anna O Burdina, Andrea M Holgado, Martine Berthelot-Grosjean, Brian D Ackley, Gayla Hadwiger, Michael L Nonet, Robby M Weimer, Janet E Richmond
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-07-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.0040261

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https://doi.org/10.1371/journal.pbio.0040261

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