Rationale and design of an independent randomised controlled trial evaluating the effectiveness of aripiprazole or haloperidol in combination with clozapine for treatment-resistant schizophrenia

Rationale and design of an independent randomised controlled trial evaluating the effectiveness of aripiprazole or haloperidol in combination with clozapine for treatment-resistant schizophrenia

<p>Abstract</p> <p>Background</p> <p>One third to two thirds of people with schizophrenia have persistent psychotic symptoms despite clozapine treatment. Under real-world circumstances, the need to provide effective therapeutic interventions to patients who do not have...

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Main Authors: Piantato Ennio, Percudani Mauro, Pecchioli Stefania, Pacilli Anna, Occhionero Guglielmo, Nicholau Stylianos, Nosè Flavio, Mulè Serena, Moretti Daniele, Mollica Marco, Migliorini Giuseppe, Menchetti Marco, Mautone Antonio, Mauri Massimo, Marsilio Alessandra, Marchiaro Livio, Malvini Lara, Malchiodi Francesca, Lintas Camilla, Lazzarin Ermanna, Laddomada Francesco, Guerrini Gualtiero, Grecu Lorella, Grazian Natalia, Giupponi Giancarlo, Grassi Luigi, Giambartolomei Andrea, Garzotto Nicola, Frova Maria, Gardellin Francesco, Parise Vincenzo, Fragomeno Nicoletta, Ferro Antonio, Ferrato Farida, Ferrannini Luigi, Esposito Eleonora, Erlicher Arcadio, Ducci Giuseppe, Di Munzio Walter, Di Lorenzo Giorgio, De Francesco Michele, Dal Santo Barbara, Colombo Paola, Cipriani Andrea, Cipresso Gabriele, Cicolini Alessia, Ciammella Luisa, Cascone Liliana, Casale Marcello, Bucolo Piera, Bozzani Alberto, Boso Marianna, Bogetto Filippo, Bivi Raffaella, Bisogno Alfredo, Biancosino Bruno, Bertolazzi Gerardo, Berardi Domenico, Beneduce Rossella, Barbui Corrado, Barale Francesco, Artioli Paola, Accordini Simone, Nosè Michela, Piazza Carlo, Pontarollo Francesco, Pycha Roger, Quartesan Roberto, Rillosi Luciana, Risso Francesco, Rizzo Raffella, Rocca Paola, Roma Stefania, Rossattini Matteo, Rossi Giuseppe, Rossi Giovanni, Sala Alessandra, Santilli Claudio, Saraò Giuseppe, Sarnicola Antonio, Sartore Francesca, Scarone Silvio, Sciarma Tiziana, Siracusano Alberto, Strizzolo Stefania, Tansella Michele, Targa Gino, Tasser Annamarie, Tomasi Rodolfo, Travaglini Rossana, Veronese Antonio, Ziero Simona
Format: Article
Language:English
Published: BMC 2009-05-01
Series:Trials
Online Access:http://www.trialsjournal.com/content/10/1/31

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http://www.trialsjournal.com/content/10/1/31

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