Dynamic Heterogeneity of the Heart Valve Interstitial Cell Population in Mitral Valve Health and Disease

Dynamic Heterogeneity of the Heart Valve Interstitial Cell Population in Mitral Valve Health and Disease

The heart valve interstitial cell (VIC) population is dynamic and thought to mediate lay down and maintenance of the tri-laminar extracellular matrix (ECM) structure within the developing and mature valve throughout life. Disturbances in the contribution and distribution of valve ECM components are...

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Bibliographic Details
Main Authors: Tori E. Horne, Matthew VandeKopple, Kimberly Sauls, Sara N. Koenig, Lindsey J. Anstine, Vidu Garg, Russell A. Norris, Joy Lincoln
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
mitral valve
valve interstitial cell
activation
Vimentin
Periostin
Twist1
smooth muscle α-actin
Online Access:http://www.mdpi.com/2308-3425/2/3/214

Internet

http://www.mdpi.com/2308-3425/2/3/214

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