Dietary Intake of Rosmarinic Acid Increases Serum Inhibitory Activity in Amyloid A Aggregation and Suppresses Deposition in the Organs of Mice

Dietary Intake of Rosmarinic Acid Increases Serum Inhibitory Activity in Amyloid A Aggregation and Suppresses Deposition in the Organs of Mice

Serum amyloid A (SAA) is one of the most important precursor amyloid proteins and plays a vital step in AA amyloidosis, although the underlying aggregation mechanism has not been elucidated. Since SAA aggregation is a key step in this pathogenesis, inhibitors are useful to prevent and treat AA amylo...

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Bibliographic Details
Main Authors: Xuguang Lin, Kenichi Watanabe, Masahiro Kuragano, Yukina Kurotaki, Ushio Nakanishi, Kiyotaka Tokuraku
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
Amyloid A amyloidosis
serum amyloid A
amyloid β
<i>Melissa officinalis</i>
microliter-scale high-throughput screening system
rosmarinic acid
Online Access:https://www.mdpi.com/1422-0067/21/17/6031

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https://www.mdpi.com/1422-0067/21/17/6031

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