Quantitation of isobaric phosphatidylcholine species in human plasma using a hybrid quadrupole linear ion-trap mass spectrometer[S]

Quantitation of isobaric phosphatidylcholine species in human plasma using a hybrid quadrupole linear ion-trap mass spectrometer[S]

Phosphatidylcholine (PC) species in human plasma are used as biomarkers of disease. PC biomarkers are often limited by the inability to separate isobaric PCs. In this work, we developed a targeted shotgun approach for analysis of isobaric and isomeric PCs. This approach is comprised of two MS method...

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Bibliographic Details
Main Authors: Petr Zacek, Michael Bukowski, Thad A. Rosenberger, Matthew Picklo
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Journal of Lipid Research
Subjects:
triple quadrupole/ion-trap
National Institute of Standards and Technology human blood plasma
mass spectrometry
shotgun lipidomics
docosahexaenoic acid
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520345491

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http://www.sciencedirect.com/science/article/pii/S0022227520345491

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