Categorisation of patients based on immune profiles: a new approach to identifying candidates for response to checkpoint inhibitors

Categorisation of patients based on immune profiles: a new approach to identifying candidates for response to checkpoint inhibitors

Abstract Objectives Inhibitors to the checkpoint proteins cytotoxic T‐lymphocyte‐associated protein 4 (CTLA‐4) and programmed cell death protein 1 (PD‐1) are becoming widely used in cancer treatment. However, a lack of understanding of the patient response to treatment limits accurate identification...

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Bibliographic Details
Main Authors: Svetlana Bornschlegl, Michael P Gustafson, Danae A Delivanis, Mabel Ryder, Minetta C Liu, George Vasmatzis, Chris L Hallemeier, Sean S Park, Lewis R Roberts, Ian F Parney, Diane F Jelinek, Allan B Dietz
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical & Translational Immunology
Subjects:
checkpoint inhibitors
CTLA‐4
immune monitoring
immune profile
PD‐1
programmed death 1
Online Access:https://doi.org/10.1002/cti2.1267

Internet

https://doi.org/10.1002/cti2.1267

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