Dynamic gene regulatory network reconstruction and analysis based on clinical transcriptomic data of colorectal cancer

Inferring dynamic regulatory networks that rewire at different stages is a reasonable way to understand the mechanisms underlying cancer development. In this study, we reconstruct the stage-specific gene regulatory networks (GRNs) for colorectal cancer to understand dynamic changes of gene regulatio...

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Bibliographic Details
Main Authors: Ancheng Deng, Xiaoqiang Sun
Format: Article
Language:English
Published: AIMS Press 2020-05-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2020183?viewType=HTML