PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions.

G protein-coupled receptors (GPCRs) constitute the largest family of membrane proteins in the human genome. Their signaling is regulated by scaffold proteins containing PDZ domains, but although these interactions are important for GPCR function, they are still poorly understood. We here present a q...

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Bibliographic Details
Main Authors: Thor C Møller, Volker F Wirth, Nina I Roberts, Julia Bender, Anders Bach, Birgitte P S Jacky, Kristian Strømgaard, Jan M Deussing, Thue W Schwartz, Karen L Martinez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23691031/?tool=EBI