A Systematic Investigation on Complement Pathway Activation in Diabetic Retinopathy

A Systematic Investigation on Complement Pathway Activation in Diabetic Retinopathy

The complement system plays a crucial role in retinal homeostasis. While the proteomic analysis of ocular tissues in diabetic retinopathy (DR) has shown the deposition of complement proteins, their exact role in the pathogenesis of DR is yet unclear. We performed a detailed investigation of the role...

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Bibliographic Details
Main Authors: Shahna Shahulhameed, Sushma Vishwakarma, Jay Chhablani, Mudit Tyagi, Rajeev R. Pappuru, Saumya Jakati, Subhabrata Chakrabarti, Inderjeet Kaur
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
retina
diabetic retinopathy
complement pathway
inflammation
microglia
angiogenesis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00154/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00154/full

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