Measuring evolutionary rates of proteins in a structural context [version 2; referees: 4 approved]

We describe how to measure site-specific rates of evolution in protein-coding genes and how to correlate these rates with structural features of the expressed protein, such as relative solvent accessibility, secondary structure, or weighted contact number. We present two alternative approaches to ra...

Full description

Bibliographic Details
Main Authors: Dariya K. Sydykova, Benjamin R. Jack, Stephanie J. Spielman, Claus O. Wilke
Format: Article
Language:English
Published: F1000 Research Ltd 2018-02-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/6-1845/v2