Stereoselective Reduction of Imines with Trichlorosilane Using Solid-Supported Chiral Picolinamides

Stereoselective Reduction of Imines with Trichlorosilane Using Solid-Supported Chiral Picolinamides

The stereoselective reduction of imines with trichlorosilane catalyzed by chiral Lewis bases is a well-established procedure for the synthesis of enantio-enriched amines. Five supported cinchona-based picolinamides have been prepared and their activity tested in a model reaction. The comparison of d...

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Bibliographic Details
Main Authors: Sílvia D. Fernandes, Riccardo Porta, Pedro C. Barrulas, Alessandra Puglisi, Anthony J. Burke, Maurizio Benaglia
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Molecules
Subjects:
supported catalysis
catalytic reactors
trichlorosilane
chiral picolinamides
organocatalysis
flow chemistry
Online Access:http://www.mdpi.com/1420-3049/21/9/1182

Internet

http://www.mdpi.com/1420-3049/21/9/1182

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