Stereoselective Reduction of Imines with Trichlorosilane Using Solid-Supported Chiral Picolinamides

Stereoselective Reduction of Imines with Trichlorosilane Using Solid-Supported Chiral Picolinamides

The stereoselective reduction of imines with trichlorosilane catalyzed by chiral Lewis bases is a well-established procedure for the synthesis of enantio-enriched amines. Five supported cinchona-based picolinamides have been prepared and their activity tested in a model reaction. The comparison of d...

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Bibliographic Details
Main Authors:	Sílvia D. Fernandes, Riccardo Porta, Pedro C. Barrulas, Alessandra Puglisi, Anthony J. Burke, Maurizio Benaglia
Format:	Article
Language:	English
Published:	MDPI AG 2016-09-01
Series:	Molecules
Subjects:	supported catalysis catalytic reactors trichlorosilane chiral picolinamides organocatalysis flow chemistry
Online Access:	http://www.mdpi.com/1420-3049/21/9/1182

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