Impaired functionality of antiviral T cells in G-CSF mobilized stem cell donors: implications for the selection of CTL donor.

Adoptive transfer of antiviral T cells enhances immune reconstitution and decreases infectious complications after stem cell transplantation. Information on number and function of antiviral T cells in stem cell grafts is scarce. We investigated (1) immunomodulatory effects of G-CSF on antiviral T ce...

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Main Authors: Carola E Bunse, Sylvia Borchers, Pavankumar R Varanasi, Sabine Tischer, Constança Figueiredo, Stephan Immenschuh, Ulrich Kalinke, Ulrike Köhl, Lilia Goudeva, Britta Maecker-Kolhoff, Arnold Ganser, Rainer Blasczyk, Eva M Weissinger, Britta Eiz-Vesper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3850912?pdf=render