Increased Hydrostatic Pressure Promotes Primary M1 Reaction and Secondary M2 Polarization in Macrophages

Increased Hydrostatic Pressure Promotes Primary M1 Reaction and Secondary M2 Polarization in Macrophages

Patients with chronic anterior uveitis are at particularly high risk of developing secondary glaucoma when corticosteroids [e.g., dexamethasone (Dex)] are used or when inflammatory activity has regressed. Macrophage migration into the eye increases when secondary glaucoma develops and may play an im...

Full description

Bibliographic Details
Main Authors: Bo Wang, Maren Kasper, Björn Laffer, Gerd Meyer zu Hörste, Susanne Wasmuth, Martin Busch, Tida Viola Jalilvand, Solon Thanos, Arnd Heiligenhaus, Dirk Bauer, Carsten Heinz
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
macrophage
increased hydrostatic pressure
secondary glaucoma
dexamethasone (DEX)
ECM-extracellular matrix
M1/M2 balance
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.573955/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.573955/full

Similar Items