Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity.

Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity.

Polycomb group proteins are transcriptional repressors that play a central role in the establishment and maintenance of gene expression patterns during development. Using mice with an N-ethyl-N-nitrosourea (ENU)-induced mutation in Suppressor of Zeste 12 (Suz12), a core component of Polycomb Repress...

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Main Authors: Ian J Majewski, Marnie E Blewitt, Carolyn A de Graaf, Edward J McManus, Melanie Bahlo, Adrienne A Hilton, Craig D Hyland, Gordon K Smyth, Jason E Corbin, Donald Metcalf, Warren S Alexander, Douglas J Hilton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18416604/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18416604/?tool=EBI

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