RELATIONSHIP BETWEEN EXPRESSION OF MATRIX METALLOPROTEINASES AND MORPHOLOGICAL HETEROGENEITY, TUMOR DIFFERENTIATION AND LYMPHOGENOUS METASTASIS OF SQUAMOUS CELL LARYNGEAL CARCINOMA

RELATIONSHIP BETWEEN EXPRESSION OF MATRIX METALLOPROTEINASES AND MORPHOLOGICAL HETEROGENEITY, TUMOR DIFFERENTIATION AND LYMPHOGENOUS METASTASIS OF SQUAMOUS CELL LARYNGEAL CARCINOMA

The study included 58 patients with stage Т1–3N0–3M0–1 squamous cell laryngeal carcinoma. The age range was from 31 to 77 years. Patients received no cancer treatment before surgery. The expression of metalloproteinases (ММP-1, -2, -9), their inhibitors (TIMP-1, -2) and inductor of metalloproteinase...

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Bibliographic Details
Main Authors: О. V. Savenkova, M. V. Zavyalova, V. A. Bychkov, Е. L. Choinzonov, V. M. Perelmuter
Format: Article
Language:Russian
Published: Tomsk National Research Medical Center of the Russian Academy of Sciences 2016-02-01
Series:Sibirskij Onkologičeskij Žurnal
Subjects:
laryngeal squamous cell carcinoma
heterogeneity of morphological structure
metalloproteinase expression
lymphogenous metastasis
Online Access:https://www.siboncoj.ru/jour/article/view/109

Internet

https://www.siboncoj.ru/jour/article/view/109

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