RELATIONSHIP BETWEEN EXPRESSION OF MATRIX METALLOPROTEINASES AND MORPHOLOGICAL HETEROGENEITY, TUMOR DIFFERENTIATION AND LYMPHOGENOUS METASTASIS OF SQUAMOUS CELL LARYNGEAL CARCINOMA
The study included 58 patients with stage Т1–3N0–3M0–1 squamous cell laryngeal carcinoma. The age range was from 31 to 77 years. Patients received no cancer treatment before surgery. The expression of metalloproteinases (ММP-1, -2, -9), their inhibitors (TIMP-1, -2) and inductor of metalloproteinase...
Main Authors: | О. V. Savenkova, M. V. Zavyalova, V. A. Bychkov, Е. L. Choinzonov, V. M. Perelmuter |
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Format: | Article |
Language: | Russian |
Published: |
Tomsk National Research Medical Center of the Russian Academy of Sciences
2016-02-01
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Series: | Sibirskij Onkologičeskij Žurnal |
Subjects: | |
Online Access: | https://www.siboncoj.ru/jour/article/view/109 |
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