Traceless Redox-Annulations of Alicyclic Amines
Amines such as 1,2,3,4-tetrahydroisoquinoline undergo redox-neutral annulations with ortho-(nitromethyl)benzaldehyde. Benzoic acid acts as a promoter in these reactions, which involve concurrent amine α-C–H bond and N–H bond functionalization. Subsequent removal of the nitro group provides access...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Georg Thieme Verlag KG
2020-10-01
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Series: | SynOpen |
Subjects: | |
Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1706004 |