Tumor-Stroma-Inflammation Networks Promote Pro-metastatic Chemokines and Aggressiveness Characteristics in Triple-Negative Breast Cancer

Tumor-Stroma-Inflammation Networks Promote Pro-metastatic Chemokines and Aggressiveness Characteristics in Triple-Negative Breast Cancer

The tumor microenvironment (TME) plays key roles in promoting disease progression in the aggressive triple-negative subtype of breast cancer (TNBC; Basal/Basal-like). Here, we took an integrative approach and determined the impact of tumor-stroma-inflammation networks on pro-metastatic phenotypes in...

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Bibliographic Details
Main Authors: Yulia Liubomirski, Shalom Lerrer, Tsipi Meshel, Linor Rubinstein-Achiasaf, Dina Morein, Stefan Wiemann, Cindy Körner, Adit Ben-Baruch
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
cancer-associated fibroblasts
CCL2
CCL5
CXCL8
interleukin 1β
mesenchymal stem cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00757/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00757/full

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