Genomic diversity among drug sensitive and multidrug resistant isolates of Mycobacterium tuberculosis with identical DNA fingerprints.

Genomic diversity among drug sensitive and multidrug resistant isolates of Mycobacterium tuberculosis with identical DNA fingerprints.

BACKGROUND:Mycobacterium tuberculosis complex (MTBC), the causative agent of tuberculosis (TB), is characterized by low sequence diversity making this bacterium one of the classical examples of a genetically monomorphic pathogen. Because of this limited DNA sequence variation, routine genotyping of...

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Main Authors: Stefan Niemann, Claudio U Köser, Sebastien Gagneux, Claudia Plinke, Susanne Homolka, Helen Bignell, Richard J Carter, R Keira Cheetham, Anthony Cox, Niall A Gormley, Paula Kokko-Gonzales, Lisa J Murray, Roberto Rigatti, Vincent P Smith, Felix P M Arends, Helen S Cox, Geoff Smith, John A C Archer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2756628?pdf=render

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http://europepmc.org/articles/PMC2756628?pdf=render

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