PAPP‐A functions as a tumor suppressor and is downregulated in renal cell carcinoma

Pregnancy‐associated plasma protein A (PAPP‐A) is a proteolytic enzyme produced by the placenta. The expression and role of PAPP‐A in renal cell carcinoma (RCC) remain elusive. The aim of this study was to investigate the role and the molecular mechanisms of PAPP‐A in RCC. Initially, we evaluated th...

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Bibliographic Details
Main Authors: Yanxin Lu, Shi Li, Tongyu Wang, Ximian Liao, Longyi Mao, Zesong Li
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.13156