Investigation on the processing and improving the cleavage efficiency of furin cleavage sites in Pichia pastoris

Investigation on the processing and improving the cleavage efficiency of furin cleavage sites in Pichia pastoris

Abstract Background Proprotein convertase furin is responsible for the processing of a wide variety of precursors consisted of signal peptide, propeptide and mature peptide in mammal. Many precursors processed by furin have important physiological functions and can be recombinantly expressed in Pich...

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Bibliographic Details
Main Authors: Yide Huang, Yanyu Long, Suhuan Li, Ting Lin, Jingwen Wu, Yafei Zhang, Yao Lin
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Microbial Cell Factories
Subjects:
Furin
Pichia pastoris
Furin cleavage site
Proprotein convertase
Kex2
YPS1
Online Access:http://link.springer.com/article/10.1186/s12934-018-1020-x

Internet

http://link.springer.com/article/10.1186/s12934-018-1020-x

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