The Neurotoxic Tau45-230 Fragment Accumulates in Upper and Lower Motor Neurons in Amyotrophic Lateral Sclerosis Subjects
Abstract Amyotrophic lateral sclerosis (ALS) is a progressive and lethal neurodegenerative disease characterized by loss of upper and lower motor neurons leading to muscle paralysis in affected individuals. Numerous mechanisms have been implicated in the death of these neurons. However, the pathobio...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2016-08-01
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| Series: | Molecular Medicine |
| Online Access: | http://link.springer.com/article/10.2119/molmed.2016.00095 |