Dengue virus activates polyreactive, natural IgG B cells after primary and secondary infection.

Dengue virus activates polyreactive, natural IgG B cells after primary and secondary infection.

BACKGROUND: Dengue virus is transmitted by mosquitoes and has four serotypes. Cross-protection to other serotypes lasting for a few months is observed following infection with one serotype. There is evidence that low-affinity T and/or B cells from primary infections contribute to the severe syndrome...

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Main Authors: Thavamalar Balakrishnan, Dennis B Bela-Ong, Ying Xiu Toh, Marie Flamand, Shamala Devi, Mickey B Koh, Martin L Hibberd, Eng Eong Ooi, Jenny G Low, Yee Sin Leo, Feng Gu, Katja Fink
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3245273?pdf=render

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http://europepmc.org/articles/PMC3245273?pdf=render

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