Tumorigenicity studies of induced pluripotent stem cell (iPSC)-derived retinal pigment epithelium (RPE) for the treatment of age-related macular degeneration.

Basic studies of human pluripotential stem cells have advanced rapidly and stem cell products are now seeing therapeutic applications. However, questions remain regarding the tumorigenic potential of such cells. Here, we report the tumorigenic potential of induced pluripotent stem cell (iPSC)-derive...

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Bibliographic Details
Main Authors: Hoshimi Kanemura, Masahiro J Go, Masayuki Shikamura, Naoki Nishishita, Noriko Sakai, Hiroyuki Kamao, Michiko Mandai, Chikako Morinaga, Masayo Takahashi, Shin Kawamata
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24454843/pdf/?tool=EBI