Preparedness against pandemic influenza: Production of an oil-in-water emulsion adjuvant in Brazil.

Increasing pandemic influenza vaccine manufacturing capacity is considered strategic by WHO. Adjuvant use is key in this strategy in order to spare the vaccine doses and by increasing immune protection. We describe here the production and stability studies of a squalene based oil-in-water emulsion,...

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Bibliographic Details
Main Authors: Milena Apetito Akamatsu, Vitor Anselmo Sakihara, Bianca Pereira Carvalho, Aline de Paiva Abrantes, Maria A Sakauchi Takano, Eduardo Alfredo Adami, Fernando Seiji Yonehara, Patrícia Dos Santos Carneiro, Stefanni Rico, Alessandra Schanoski, Maurício Meros, Adrian Simpson, Tony Phan, Christopher B Fox, Paulo Lee Ho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0233632