Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation

Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation

Prereplicative complex (pre-RC) formation during G1 is fundamental for cell replication. Here the authors report a role for cyclin K in regulating pre-RC formation in mammalian cells by affecting cyclin E1 activity.

Bibliographic Details
Main Authors: Tingjun Lei, Peixuan Zhang, Xudong Zhang, Xue Xiao, Jingli Zhang, Tong Qiu, Qian Dai, Yujun Zhang, Ling Min, Qian Li, Rutie Yin, Ping Ding, Ni Li, Yi Qu, Dezhi Mu, Jun Qin, Xiaofeng Zhu, Zhi-Xiong Xiao, Qintong Li
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-04258-w

Internet

https://doi.org/10.1038/s41467-018-04258-w

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