Further evidence for functional recovery of AQP2 mutations associated with nephrogenic diabetes insipidus

Further evidence for functional recovery of AQP2 mutations associated with nephrogenic diabetes insipidus

Abstract Aquaporin‐2 (AQP2) is a homotetrameric water channel responsible for the final water reuptake in the kidney. Disease‐causing AQP2 mutations induce nephrogenic diabetes insipidus (NDI), a condition that challenges the bodily water balance by producing large urinary volumes. In this study, we...

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Bibliographic Details
Main Authors: Pierre Bissonnette, Yoann Lussier, Jessica Matar, Alexandre Leduc‐Nadeau, Sandra Da Cal, Marie‐Françoise Arthus, Robert J. Unwin, Julia Steinke, Dharshan Rangaswamy, Daniel G. Bichet
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Physiological Reports
Subjects:
aquaporin‐2
functional recovery
nephrogenic diabetes insipidus
recessive mutations
Online Access:https://doi.org/10.14814/phy2.14866

Internet

https://doi.org/10.14814/phy2.14866

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