Deletion of murine slc29a4 modifies vascular responses to adenosine and 5‐hydroxytryptamine in a sexually dimorphic manner

Deletion of murine slc29a4 modifies vascular responses to adenosine and 5‐hydroxytryptamine in a sexually dimorphic manner

Abstract Equilibrative nucleoside transporter 4 (ENT4), encoded by SLC29A4, mediates the flux of both 5‐hydroxytryptamine (5‐HT) and adenosine across cell membranes. We hypothesized that loss of ENT4 function in mice would modify the effects of these established regulators of vascular function. Male...

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Bibliographic Details
Main Authors: Ran Wei, Stephen L. Gust, David Tandio, Alexia Maheux, Khanh H. Nguyen, Joanne Wang, Stephane Bourque, Frances Plane, James R. Hammond
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Physiological Reports
Subjects:
5‐HT
adenosine
mesenteric artery
transporters
vascular
Online Access:https://doi.org/10.14814/phy2.14395

Internet

https://doi.org/10.14814/phy2.14395

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