Macrophages and microglia: the cerberus of glioblastoma

Abstract Glioblastoma (GBM) is the most aggressive and deadliest of the primary brain tumors, characterized by malignant growth, invasion into the brain parenchyma, and resistance to therapy. GBM is a heterogeneous disease characterized by high degrees of both inter- and intra-tumor heterogeneity. A...

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Bibliographic Details
Main Authors: Alice Buonfiglioli, Dolores Hambardzumyan
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Acta Neuropathologica Communications
Subjects:
Online Access:https://doi.org/10.1186/s40478-021-01156-z