Neurites containing the neurofilament-triplet proteins are selectively vulnerable to cytoskeletal pathology in Alzheimer’s disease and transgenic mouse models
Amyloid-β plaque accumulation in Alzheimer’s disease (AD) is associated with dystrophic neurite formation and synapse loss in principal neurons, but interneuron pathology is less clearly characterised. We compared the responses of neuronal processes immunoreactive for either neurofilament triplet (N...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2013-09-01
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Series: | Frontiers in Neuroanatomy |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnana.2013.00030/full |