Development of a novel heterologous β-lactam-specific whole-cell biosensor in Bacillus subtilis

Abstract Background Whole-cell biosensors are a powerful and easy-to-use screening tool for the fast and sensitive detection of chemical compounds, such as antibiotics. β-Lactams still represent one of the most important antibiotic groups in therapeutic use. They interfere with late stages of the ba...

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Bibliographic Details
Main Authors: Nina Lautenschläger, Philipp F. Popp, Thorsten Mascher
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Journal of Biological Engineering
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13036-020-00243-4