Mucosal Heterologous Prime/Boost Vaccination Induces Polyfunctional Systemic Immunity, Improving Protection Against Trypanosoma cruzi

Mucosal Heterologous Prime/Boost Vaccination Induces Polyfunctional Systemic Immunity, Improving Protection Against Trypanosoma cruzi

There are several unmet needs in modern immunology. Among them, vaccines against parasitic diseases and chronic infections lead. Trypanosoma cruzi, the causative agent of Chagas disease, is an excellent example of a silent parasitic invasion that affects millions of people worldwide due to its progr...

Full description

Bibliographic Details
Main Authors: Andrés Sanchez Alberti, Augusto E. Bivona, Marina N. Matos, Natacha Cerny, Kai Schulze, Sebastian Weißmann, Thomas Ebensen, Germán González, Celina Morales, Alejandro C. Cardoso, Silvia I. Cazorla, Carlos A. Guzmán, Emilio L. Malchiodi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
neglected tropical disease
Chagas disease
Anti-Trypanosoma cruzi vaccine
prime-boost vaccine
Traspain
cyclic-di-AMP
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00128/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00128/full

Similar Items