Differential Neuroplastic Changes in Fibromyalgia and Depression Indexed by Up-Regulation of Motor Cortex Inhibition and Disinhibition of the Descending Pain System: An Exploratory Study

Background: Major depressive disorder (MDD) and fibromyalgia (FM) present overlapped symptoms. Although the connection between these two disorders has not been elucidated yet, the disruption of neuroplastic processes that mediate the equilibrium in the inhibitory systems stands out as a possible mec...

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Main Authors: Tiago Madeira Cardinal, Luciana Conceição Antunes, Aline Patricia Brietzke, Cristiane Schulz Parizotti, Fabiana Carvalho, Andressa De Souza, Iraci Lucena da Silva Torres, Felipe Fregni, Wolnei Caumo
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Human Neuroscience
Subjects:
CPM
Online Access:https://www.frontiersin.org/article/10.3389/fnhum.2019.00138/full