Can Integrin Agonists Have Cards to Play against Cancer? A Literature Survey of Small Molecules Integrin Activators

Can Integrin Agonists Have Cards to Play against Cancer? A Literature Survey of Small Molecules Integrin Activators

The ability of integrins to activate and integrate intracellular communication illustrates the potential of these receptors to serve as functional distribution hubs in a bi-directional signal transfer outside-in and inside-out of the cells. Tight regulation of the integrin signaling is paramount for...

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Bibliographic Details
Main Authors: Alessandra Tolomelli, Paola Galletti, Monica Baiula, Daria Giacomini
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Cancers
Subjects:
integrins
agonists
ligands
signaling
lactams
RGD mimetics
activation
Online Access:https://www.mdpi.com/2072-6694/9/7/78

Internet

https://www.mdpi.com/2072-6694/9/7/78

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