The Potential of Soluble Human Leukocyte Antigen Molecules for Early Cancer Detection and Therapeutic Vaccine Design

Human leukocyte antigen (HLA) molecules are essential for anti-tumor immunity, as they display tumor-derived peptides to drive tumor eradication by cytotoxic T lymphocytes. HLA molecules are primarily studied as peptide-loaded complexes on cell membranes (mHLA) and much less attention is given to th...

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Bibliographic Details
Main Authors: Amy L. Kessler, Marco J. Bruno, Sonja I. Buschow
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/8/4/775