Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients

<p>Abstract</p> <p>Background</p> <p>The diagnostic and pathophysiological relevance of antibodies to aquaporin-4 (AQP4-Ab) in patients with neuromyelitis optica spectrum disorders (NMOSD) has been intensively studied. However, little is known so far about the clinical...

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Main Authors: Jarius Sven, Ruprecht Klemens, Wildemann Brigitte, Kuempfel Tania, Ringelstein Marius, Geis Christian, Kleiter Ingo, Kleinschnitz Christoph, Berthele Achim, Brettschneider Johannes, Hellwig Kerstin, Hemmer Bernhard, Linker Ralf A, Lauda Florian, Mayer Christoph A, Tumani Hayrettin, Melms Arthur, Trebst Corinna, Stangel Martin, Marziniak Martin, Hoffmann Frank, Schippling Sven, Faiss Jürgen H, Neuhaus Oliver, Ettrich Barbara, Zentner Christian, Guthke Kersten, Hofstadt-van Oy Ulrich, Reuss Reinhard, Pellkofer Hannah, Ziemann Ulf, Kern Peter, Wandinger Klaus P, Bergh Florian, Boettcher Tobias, Langel Stefan, Liebetrau Martin, Rommer Paulus S, Niehaus Sabine, Münch Christoph, Winkelmann Alexander, Zettl U Uwe K, Metz Imke, Veauthier Christian, Sieb Jörn P, Wilke Christian, Hartung Hans P, Aktas Orhan, Paul Friedemann
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://www.jneuroinflammation.com/content/9/1/14