Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis

Lineage segregation from conception to gastrulation has been mapped at the single cell level in mouse, human and monkey. Here, the authors provide a comprehensive analysis of porcine preimplantation development using single cell RNA-seq; mapping metabolic changes, X chromosome inactivation and signa...

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Bibliographic Details
Main Authors: Priscila Ramos-Ibeas, Fei Sang, Qifan Zhu, Walfred W. C. Tang, Sarah Withey, Doris Klisch, Liam Wood, Matt Loose, M. Azim Surani, Ramiro Alberio
Format: Article
Language:English
Published: Nature Publishing Group 2019-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08387-8