Role of STAT3 in hepatocyte regeneration after acetaminophen-induced hepatocellular injury in mice

ObjectiveTo investigate the role of STAT3 in hepatocyte proliferation after acetaminophen (APAP)-induced hepatocellular injury in mice. MethodsNormal mouse AML12 hepatocytes were cultured in vitro and were stimulated by APAP (1, 2.5, 5, 10, and 20 mmol/L) for 12, 24 or 48 hours, and the hepatocytes...

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Bibliographic Details
Main Author: YU Wang
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Hepatology 2021-04-01
Series:Linchuang Gandanbing Zazhi
Online Access:http://www.lcgdbzz.org/cn/article/doi/10.3969/j.issn.1001-5256.2021.04.026