Reduced synaptic activity in neuronal networks derived from embryonic stem cells of murine Rett syndrome model

Neurodevelopmental diseases such as the Rett syndrome have received renewed attention, since the mechanisms involved may underlie a broad range of neuropsychiatric disorders such as schizophrenia and autism. In vertebrates early stages in the functional development of neurons and neuronal networks a...

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Bibliographic Details
Main Authors: Lydia eBarth, Rosmarie eSütterlin, Markus eNenniger, Kaspar Emanuel Vogt
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00079/full