Relevance of baseline viral genetic heterogeneity and host factors for treatment outcome prediction in hepatitis C virus 1b-infected patients.

BACKGROUND:Only about 50% of patients chronically infected with HCV genotype 1 (HCV-1) respond to treatment with pegylated interferon-alfa and ribavirin (dual therapy), and protease inhibitors have to be administered together with these drugs increasing costs and side-effects. We aimed to develop a...

Full description

Bibliographic Details
Main Authors: Verónica Saludes, Elisabet Bascuñana, Elena Jordana-Lluch, Sònia Casanovas, Mercè Ardèvol, Esther Soler, Ramón Planas, Vicente Ausina, Elisa Martró
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3755994?pdf=render