Activation of hypoxia inducible factor 1 is a general phenomenon in infections with human pathogens.

Activation of hypoxia inducible factor 1 is a general phenomenon in infections with human pathogens.

BACKGROUND: Hypoxia inducible factor (HIF)-1 is the key transcriptional factor involved in the adaptation process of cells and organisms to hypoxia. Recent findings suggest that HIF-1 plays also a crucial role in inflammatory and infectious diseases. METHODOLOGY/PRINCIPAL FINDINGS: Using patient ski...

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Main Authors: Nadine Werth, Christiane Beerlage, Christian Rosenberger, Amir S Yazdi, Markus Edelmann, Amro Amr, Wanja Bernhardt, Christof von Eiff, Karsten Becker, Andrea Schäfer, Andreas Peschel, Volkhard A J Kempf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2904385?pdf=render

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http://europepmc.org/articles/PMC2904385?pdf=render

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