Sulforaphene induces apoptosis and inhibits the invasion of esophageal cancer cells through MSK2/CREB/Bcl-2 and cadherin pathway in vivo and in vitro

Sulforaphene induces apoptosis and inhibits the invasion of esophageal cancer cells through MSK2/CREB/Bcl-2 and cadherin pathway in vivo and in vitro

Abstract Background As a novel type of isothiocyanate derived from radish seeds from cruciferous vegetables, sulforaphene (SFE, 4-methylsufinyl-3-butenyl isothiocyanate) has various important biological effects, such as anti-oxidative and anti-bacterial effects. Recently, sulforaphene has attracted...

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Bibliographic Details
Main Authors: Chengjuan Zhang, Junxia Zhang, Qiong Wu, Benling Xu, Guoguo Jin, Yan Qiao, Simin Zhao, Yang Yang, Jinwen Shang, Xiaofang Li, Kangdong Liu
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Cancer Cell International
Subjects:
Sulforaphene
Esophageal cancer
Apoptosis
Invasion
MSK2
Online Access:https://doi.org/10.1186/s12935-019-1061-1

Internet

https://doi.org/10.1186/s12935-019-1061-1

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