Fronto-striatal grey matter contributions to discrimination learning in Parkinson’s disease

Fronto-striatal grey matter contributions to discrimination learning in Parkinson’s disease

Discrimination learning deficits in Parkinson’s disease (PD) have been well established. Using both behavioural patient studies and computational approaches, these deficits have typically been attributed to dopamine imbalance across the basal ganglia. However, this explanation of impaired learning i...

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Bibliographic Details
Main Authors: Claire eO'Callaghan, Ahmed A Moustafa, Sanne ede Wit, James M Shine, Trevor W Robbins, Simon J. G Lewis, Michael eHornberger
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Computational Neuroscience
Subjects:
Discrimination Learning
Parkinson’s disease
Computational modelling
Voxel-based morphometry (VBM)
goal-directed learning
fronto-striatal
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncom.2013.00180/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncom.2013.00180/full

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