An Autocrine Wnt5a Loop Promotes NF-κB Pathway Activation and Cytokine/Chemokine Secretion in Melanoma

An Autocrine Wnt5a Loop Promotes NF-κB Pathway Activation and Cytokine/Chemokine Secretion in Melanoma

Wnt5a signaling has been implicated in the progression of cancer by regulating multiple cellular processes, largely migration and invasion, epithelial-mesenchymal transition (EMT), and metastasis. Since Wnt5a signaling has also been involved in inflammatory processes in infectious and inflammatory d...

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Bibliographic Details
Main Authors: Gastón Barbero, María Victoria Castro, María Belén Villanueva, María Josefina Quezada, Natalia Brenda Fernández, Sharon DeMorrow, Pablo Lopez-Bergami
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
Wnt5a
NF-κB
Akt
melanoma
cytokine
chemokine
Online Access:https://www.mdpi.com/2073-4409/8/9/1060

Internet

https://www.mdpi.com/2073-4409/8/9/1060

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