Efficacy and dose-dependent safety of intra-arterial delivery of mesenchymal stem cells in a rodent stroke model.

Efficacy and dose-dependent safety of intra-arterial delivery of mesenchymal stem cells in a rodent stroke model.

Intra-arterial (IA) delivery of mesenchymal stem cells (MSCs) for acute ischemic stroke is attractive for clinical translation. However, studies using rat model of stroke have demonstrated that IA MSCs delivery can decrease middle cerebral artery (MCA) flow, which may limit its clinical translation....

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Bibliographic Details
Main Authors: Dileep R Yavagal, Baowan Lin, Ami P Raval, Philip S Garza, Chuanhui Dong, Weizhao Zhao, Erika B Rangel, Ian McNiece, Tatjana Rundek, Ralph L Sacco, Miguel Perez-Pinzon, Joshua M Hare
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24807059/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24807059/?tool=EBI

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